Scientific Program – Draft – 33rd International Symposium on Pharmaceutical and Biomedical Analysis

July 2, 2023
	Lecture Halls
07.30-17.00	Registration
10.00-10.45	Courses
10.45-11.00	Coffee Break
11.00-12.30	Courses
12.30-13.30	Lunch
13.30-15.00	Courses
17.00-17.45	Opening Ceremony
17.45-18.30	PL 1 – Bezhan Chankvetadze Recent Challenges and Trends in Enantioselective Analysis of Chiral Drugs
19.15-21.00	Welcome Reception

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July 3, 2023
	Hall A
09.00-09.45	PL 2 – Frantisek Svec (Hi)story of chromatography: Monoliths
09.45-10.00	Coffee Break
	Hall A	Hall B
10.00-10.30	KL 1 – Szabolcs Beni	KL 2 – Ann Van Schepdael Impact of sterilization on the chemical composition of a selection of active pharmaceutical ingredients
10.30-11.00	KL 3 – Emmanuelle Lipka From analytical to preparative scale in chiral supercritical fluid chromatography: economy, challenge, opportunity	KL 4 – Sandra Furlanetto New trends in Quality Control: New compendial and ICH guidelines outlining Quality by Design (QbD) principles
11.00-11.20	IL 1 – Paola Peluso Integrating experimental and computational approaches to study enantioselective recognition in liquid-phase enantioseparations	IL 2 – Vladimir Ioffe Not Only Reverse Phase… A Need to Use Alternative HPLC Techniques for Pharmaceutical Analysis
11.20-11.35	OP 1 – Tamar Khatiashvili Photochemical immobilization of cellulose tris(3-chloro-5-methylphenylcarbamate) on silica and its use for separation of enantiomers in high-performance liquid chromatography	OP 2 – Chee-Leong Kee Analytical methodologies and challenges in the analysis of synthetic phosphodiesterase type 5 inhibitors (PDE-5i) found as adulterants in health supplements
11.35-11.50	OP 3 – Baochun Shen The Enantiseparation of Chiral Compounds by Chiral Stationary Phases	OP 4 – Murat Özdemir Quantitative Analysis of Estradiol and Estradiol Metabolites by UPLC-MS/MS Method
11.50-13.30	Lunch and Vendor Seminars (Metrohm)
13.30-14.00	KL 5 – Gerhard Scriba Analyte Complexation and Chiral Separations in Capillary Electrophoresis	KL 6 – Attila Fellinger Thermodynamics of Liquid Chromatography
14.00-14.20	IL 3 – Antonio Salgado NMR studies on the elucidation of the (unusual) structure of selector-selectand aggregates between daclatasvir and some cyclodextrins	IL 4 – Aalessandra Gentili Adavances in Solid Phase Extraction: the evolution of carbon-based sorbents
14.20-14.35	OP 5 – Ann Gogolashvili Mechanistic studies on enantioselective noncovalent selector-selectand interactions using capillary electrophoresis, nuclear magnetic resonance spectroscopy and isothermal titration microcalorimetry	OP 6 – Lukasz Ciesla Novel solutions in drug discovery from complex natural matrices for the prevention and treatment of neurodegenerative diseases
14.35-14.50	OP 7 – Pavel Jáč Development of capillary electrophoresis-mass spectrometry method for the simultaneous analysis of boswellic acids and non-steroidal anti-inflammatory drugs	OP 8 – Dönay Yuvalı Determination of Tamoxifen in Biological Fluids Using Liquid-Phase Microextraction and Liquid Chromatographic Analysis
14.50-15.05	OP 9 – Nevin Öztekin Separation and determination of enantiomers of 2-hydroxyglutaric acid in urine by capillary electrophoresis with contactless conductivity detection	OP 10 – Sercan Yıldırım A deep eutectic solvent-based ferrofluid for vortex-assisted liquid-liquid microextraction of nonsteroidal anti-inflammatory drugs from environmental waters
15.05-16.15	Coffee Break and Poster Session-1
16.15-16.45	KL 7 – Kenji Hamase Three/four-Dimensional Chiral HPLC Analysis of Amino Acids in Mammals; Their Origins, Regulation Systems and Diagnostic Values	KL 8 – Zbigniew Brzozka Cell-on-a-chip microsystems – alternative in vitro models to study effectiveness of medical therapies
16.45-17.00	OP 11 – Chiharu Ishii Selective Determination of D-Amino Acids in Human Plasma Using a Two-Dimensional LC-MS/MS System Toward Early-Diagnosis of Chronic Kidney Disease	OP 12 – Sara Tengattini HILIC-MS-driven optimization of protein glycosylation via disuccinimidyl linker for pure glycoconjugate vaccine synthesis
17.00-17.15	OP 13 – Rusudan Kakava Synthesis of chiral sulfoxides and study of structure-retention and structure-enantioselectivity relationships	OP 14 – Leyla Karadurmus A molecularly imprinted polymer-based electrochemical sensor for the determination of Emtricitabine
17.15-17.30	OP 15 – Markus Ganzera Mycosporine Like Amino Acids – Isolation and Analysis of Promising Marine Sunscreens	OP 16 – Aytekin Uzunoğlu Inkjet-Printing of MXene/Holey CNT-based Inks for the Construction of Flexible Nicotine Sensors
17.30-17.45	OP 17 – F. Bedia Erim Biopolymers as antibacterial wound dressing and controlled drug release agents	OP 18 – İnci Uludağ An Immunosensor Using A Specific Aptamer as A Bioreceptor for Quantification of Sarcosine
19.00-19.30	Traditional Dance Show

July 4, 2023
	Hall A
09.00-09.45	PL 3 – Jean-Michel Kauffmann Trends in Analytical Chemistry
09.45-10.00	Coffee Break
	Hall A	Hall B	Hall C
10.00-10.30	KL 9 – Can Dincer Disposable sensors for next-generation point-of-care diagnostics	KL 10 – Andras Guttman Size, charge, and N-glycosylation variant analysis of the anti-COVID-19 monoclonal antibody bamlanivimab by capillary gel electrophoresis	KL 11 – Federico Marini
10.30-11.00	KL 12 – Alain Walcarius Interest oriented mesoporous silica films for the electrochemical detection of biologically relevant species	KL 13 – Serge Rudaz From untargeted metabolomics to longitudinal targeted monitoring in clinics	KL 14 – Ashraf Ghanem Chirality post COVID: Challenges, Adaptations, and Future Prospects
11.00-11.20	IL 5 – Bobak Mosadegh Soft Robotic Sensing Array Catheters for Cardiac Arrythmias	IL 6 – Chiara Fanali Recent results in food sample preparation employing deep eutectic solvents	IL 7 – Daniel Quesada-González Lateral Flow Tests: Signal Enhancement Methods and Future Trends for Diagnostics
11.20-11.35	OP 19 – Mehmet Bülent Özer Acoustic Particle Manipulation in 3-D Printed Acoustophoretic Microfluidic Chips	OP 20 – Mustafa Çelebier Unveiling the Metabolic Signature of Preeclampsia: A Promising Analytical Tool for Early Detection	OP 21 – Ezgi Salmanli A New Competitive Lateral Flow Immunoassay Test for Rapid Detection of Total Antibody in Vaccinated Puppies Serum Against Canine Parvovirus-2
11.35-11.50	OP 22 – Dilsat Ozkan-Ariksoysal An Overview of Current Approaches in Quantum Dot-Based Electrochemical DNA Biosensors and Their Potential for Use in the Diagnostic Kit Field	OP 23 – Jingwu Kang Drug Target identification by Integrative Analysis of Photoaffinity Labeling Chemoproteomics and Untargeted Metabolomics	OP 24 – Aysun Dinçel Simultaneous spectrophotometric analysis of emtricitabine and tenofovir disoproxil fumarate in pharmaceutical formulation
11.50-12.05	Symposium Photo
12.05-13.30	Lunch and Vendor Seminars (CAS Life Sciences and SciFinder Discovery Platform)
13.30-14.00	KL 15 – Zuhre Senturk The Story of the 100-Year Path of Voltammetry, Starting with Drops of Mercury and Reaching the Mysterious Shores of the Brain	KL 16 – Martin Vogel Electrochemistry/mass spectrometry – a versatile tool to mimic the metabolism of drug substances	KL 17 – Zhengjin Jiang Rapid purification and separation of antibody drugs based on epitope-mimetic peptide recognition technology
14.00-14.20	IL 8 – Francesco Busardo Development of enantioselective high-performance liquid chromatography-tandem mass spectrometry method for quantitative determination of methylone and some of its metabolites in oral fluid	IL 9 – Sezgin Bakırdere Trends in analytical strategies for the determination of pharmaceuticals	IL 10 – Marcello Locatelli Emerging challenges for Analytical Chemistry in the Pharmaceutical and Biomedical Analysis
14.20-14.35	OP 25 – Annagiulia Di Trana The role of analytical pharmacotoxicology in adressing the main functions of the National Early Warning System on NPS	OP 26 – Fahad S Aldawsari An analytical debate regarding nitrite analysis in raw materials associated with nitrosamine occurrence in finished products; the importance of selecting a precise testing methodology	OP 27 – Fezile Ozdemir The Effect of Pharmacokinetic Genes Polymorphisms to the Plasma Clozapine and Norclozapine Levels in Patients with Schizophrenia
14.35-14.50	OP 28 – Véronique Gilard Benchtop-NMR for the detection of undeclared drugs in e-liquids and aphrodisiac honeys	OP 29 – Onur Bender Targeting FLT3/ITD mutation in acute myeloid leukemia: lessons from natural compounds	OP 30 – Kenan Can Tok Accurate and Precise Determination of Pregabalin in Pharmaceutical Formulations and Biological Samples using HPLC-UV Methodology
14.50-15.05	OP 31 – Demet Dincel Therapeutic drug monitoring of the free and total valproic acid in human plasma by LC-MS/MS	OP 32 – N.Neslihan Bozkurt LC-MS/MS-Based Quantitative Analysis of A Tricyclic Antidepressant and Its Major Metabolite	OP 33 – Abd Al Rahman Mohammd Faez Asfour Investigation of New Thiazole Derivatives and their Biological Effects
15.05-16.15	Coffee Break and Poster Session-2
16.15-16.45	KL 18 – Davy Guillarme Innovative chromatographic strategies to improve the characterization of oligonucleotides	KL 19 – Stig Pedersen-Bjergaad Electromembrane extraction of peptides	KL 20 – Bekir Salih Current state-of-the-art Ion Mobility and Mass Spectrometry-based Analyses of Pharmaceuticals and Biomolecules
16.45-17.00	OP 34 – Guo Jialiang Screening of trypsin inhibitors in Cotinus coggygria Scop. extract using at-line nanofractionation coupled with semi-preparative reverse-phase liquid chromatography	OP 35 – Jonathan Maurer Peptide assays: an ounce of pre-analytics is worth a pound of cure	OP 36 – Nadia Bounoua An overview in the chiral separation of azole compounds using some analytical methods
17.00-17.15	OP 37 – Khaldun Mohammad Al Azzam Enhancement of Apixaban’s Solubility and Dissolution Rate by Inclusion Complex (β-Cyclodextrin and Hydroxypropyl β-Cyclodextrin) and Computational Calculation of their Inclusion Complexes	OP 38 – Joanna Bogusiewicz The lipidomic landscape of different mutations in human brain tumors.	OP 39 – Anıl Yılmaz Synthesis of Novel Oxime and Benzofuran Chemical Frameworks Possessing Potent Anticholinesterase Activity: A SAR Study Related to Alzheimer Disease
17.15-17.30	OP 40 – Zeynep Özdemir Quantification of Carbamazepine Profile in Human Plasma by GC-MS	OP 41 – Mine Ensoy Vulpinic Acid Induces Ferroptosis by Inceasing ROS Level and Changing Expression Profile of Ferroptosis Related Genes in Breast Cancer	OP 42 – Nuran Gökdere Green synthesis and characterization of silver nanoparticles using Pyracantha Coccinea M.J. Roem and their antibacterial, antibiofilm and anti quorum sensing activities
17.30-17.45	OP 43 – Üzeyir Doğan Development of a method for quantification of some metallic content of Humulus lupulus L. plant with ICP-OES	OP 44 – Canan Özyurt DEVELOPMENT of a FLUORESCENCE-BASED NUCLEIC ACID BIOSENSOR for the DETECTION of BACTERIAL PROTEASE ENZYME	OP 45 – Mohamed Nadjib Chiral Separation and Absolute Configuration Assignment of Racemic Bioactives Molecules

July 5, 2023
	Hall A
09.00-09.45	PL 4 – Janusz Pawlisyzn Development of Green Analytical Devices for Clinical and Medical Applications
09.45-10.00	Coffee Break
	Hall A	Hall B	Hall C
10.00-10.30	KL 21 – Fırat Güder	KL 22 – Rafael Lucena Biopolymer sorptive phases in bioanalysis	KL 23 – Mamas Prodromidis Wax screen printed fabric-based colorimetric microfluidic wearable biosensor for the determination of biomarkers in sweat –
10.30-11.00	KL 24 – Susana Campuzano What can bioelectroanalysis do for decentralized and sustainable precision medicine?	KL 25 – Barbara Bojko Solid phase microextraction – new diagnostic tool in transplant surgery	KL 26 – Jiri Homola
11.00-11.20	IL 11 – Esen Bellur Atıcı Synthesis, analysis, risk-knowledge-data-based process & impurity evaluation of drug substances	IL 12 – Ezel Boyacı Recent Advances in Targeted and Untargeted Metabolomics with Solid Phase Microextraction	IL 13 – M. Asunción Alonso-Lomillo Sensors on pharmaceutical and biomedical electroanalysis
11.20-11.35	OP 46 – Verónica Serafín Electroanalytical biotools to advance food allergy at different molecular levels	OP 47 – Leon Reubsaet Smart sampling: next-generation DBS samplers for LC-MS based protein analysis	OP 48 – Sineenat Siri Colorimetric aptasensor for paraquat detection based on truncated DNA aptamer and gold nanoparticles
11.35-11.50	OP 49 – S. Irem Kaya Development of selective and sensitive MIP-based electrochemical sensor for Quercetin determination from Rubus sanctus, Fragaria vesca extracts and some herbal supplements	OP 50 – Wei Zhou Recessed solid-phase microextraction acupuncture needle for in vivo tissue sampling and direct analysis by mass spectrometry via automated microfluidic open interface	OP 51 – Supamas Napavichayanun A new artificial saliva containing cumin and ginger for stimulating saliva secretion
11.50-13.00	Lunch and Vendor Seminars
	Hall A
13.00-13.45	PL 5 – Gustavo Rivas
	Hall A	Hall B	Hall C
13.45-13.55	YS 1 – Vuslat B. Juska Multiplexed miniaturised microfabricated silicon devices for electrochemical biosensing: from chemical to biological systems	YS 16 – Timothy Joseph Bushman Bacterial Espresso? Accelerated Solvent Extraction of Bacterial Cell Pellet as a Method for the Improved Extraction Recovery of Selected Metabolites	YS 31 – Pakawat Kongpreecha Development of colorimetric aptasensor for detection of 17β-estradiol in milk based on newly designed aptamers and gold nanoparticles
13.55-14.05	YS 2 – Dogus Akboga Living Biosensors with Synthetic Genetic Circuits to Monitor Nanomaterial and Heavy Metal Triggered Toxicity	YS 17 – Ummugulsum Polat Application of Magnetic Solid Phase Extraction for Sensitive and Simultaneous Analysis of Glipizide and Pravastatin Drugs in Synthetic Urine Samples with HPLC-DAD	YS 32 – Kubra Turan Development of Electrochemical Sensor Based on Glassy Carbon Electrode Modified with CeO2/PNMA/fMWCNTs composite for Simultaneous Detection of Uric Acid and 5-Fluorouracil
14.05-14.15	YS 3 – Tuğba Nur Bozkurt A novel decision support system based on feature extraction, feature ranking, feature selection for accurate diagnosis of diseases using medical images	YS 18 – Tugce Unutkan Gösterişli A liquid phase microextraction method for extraction and preconcentration of parabens in lipstick samples prior to high performance liquid chromatography – UV detection	YS 33 – Raghad Alhardan A novel electrochemical tyrosinase biosensor for the monitoring inhibition of Rosmaniric acid from plants
14.15-14.25	YS 4 – Alara Karaman Cell and Microparticle Manipulation Using Acoustic Waves in Microchannels	YS 19 – Suleyman Bodur Determination of chloroquine phosphate at trace levels in human serum, saliva and urine samples by gas chromatography–mass spectrometry after vortex assisted spraying based fine droplet formation liquid phase microextraction	YS 34 – Manolya Mujgan Gurbuz The first electrochemical sensor for the determination of Ibrutinib in human serum in the presence of anionic surfactant
14.25-14.35	YS 5 – Orelia Cerlati Insight into Aβ/membrane lipids/metal ion interplay in the context of Alzheimer’s disease	YS 20 – Sezin Erarpat Determination of Vitamin B12 in vitamin tablets by high performance liquid chromatography combined with flame atomic absorption spectrophotometry with a novel nebulizer interface supported T-shaped slotted quartz tube	YS 35 – Zeynep Caglayan Arslan Detection of Mutations on ctDNA Samples with All-MEMS Photoelectrochemical Sensor
14.35-14.45	YS 6 – Meryem Beyza Avcı Portable handheld biosensing platform for point-of-care virus detection in field settings	YS 21 – Cemil Can Eylem 18O assisted GC-MS based fluxomics analysis for central carbon metabolism intermediates in colorectal cancer cell line	YS 36 – Ulfet Erdogan Uzunoglu Determination of Liposomal Vitamin C Using Polarography
14.45-14.55	YS 7 – Ayşe Necla Akıllı Direct Determination of Surface Proteins in Leishmania	YS 22 – Şeyma Nigiz Molecular and metabolic characterization of multi-drug resistant isolates of Acinetobacter baumannii	YS 37 – Pelin Şenel Spectroscopic and electrochemical studies on the interactional of purine nucleoside antimetabolite Clofarabine with double helix deoxyribonucleic acid
14.55-15.20	Coffee Break
15.20-15.30	YS 8 – Arnon Buntha Development of fluorescent aptasensor to detect 17β-estradiol in human blood	YS 23 – Fabian Hammerle Sophisticated mass spectrometry-based techniques for the identification of novel mycosporine-like amino acids in marine organisms	YS 38 – Büşra Sevim Evaluation of Thermal and Structural Stability of Pediocin PA-1 Mutants with MD Simulations
15.30-15.40	YS 9 – Merve Çalımcı High-yield and facile genomic DNA extraction method on glass fiber strip for LAMP PCR based pathogenic bacteria detection	YS 24 – Veselina Adımcılar Fast and Sensitive Determination of Orotic Acid in Urine Samples with Capillary Electrophoresis Coupled with Contactless Conductivity Detection	YS 39 – Abdullah Al Faysal Elucidation of binding interactions and mechanism of tyrosine kinase inhibitor Axitinib with dsDNA via multi-spectroscopic and voltammetric studies
15.40-15.50	YS 10 – Nina Felli	YS 25 – Hatice Demirtas Enhancing Anticancer Potential: Optimization of Niclosamide-Loaded Lipid Nanocapsules for Improved Delivery and Quantification	YS 40 – Sevilay Erdoğan Kablan A Validated Electrochemical Method for Quantification of Molnupiravir in Capsule Dosage Forms
15.50-16.00	YS 11 – Nilay Kahya Controlled release of silver sulfadiazine from CeO₂-loaded chitosan composite films as potential wound dressings	YS 26 – Ceren H. Bozmaoglu Solid Lipid Nanoparticles Loaded with Vemurafenib: A Promising Approach for the Treatment of Metastatic Melanoma	YS 41 – Nilay Bilgin Sarıtaş Photodegradation of favipiravir and oseltamivir in the presence of microplastics
16.00-16.10	YS 12 – Meltem Okan An Upconverting Nanoparticle based Photoelectrochemical Sensor for the Detection of ctDNA	YS 27 – Lorenzo Antonelli A new nano-composite material from recycled PLA for magnetic dispersive solid-phase extraction	YS 42 – Hayrani Eren Bostancı The Effect of Vitamins on Oxidation in Experimentally Diabetes Conditioned Rats
16.10-16.20	YS 13 – Semih Çalamak Colloidal Silver Nanoparticle Color Change Determination Using Digitized RGB Intensities as a Smartphone Readout for Sensing Application	YS 28 – Nevin Ulaş Çolak Two-step microwave extraction with NADES and biological activity comparison of Origanum Michrantum and Origanum Minutiflorum Plants	YS 43 – Husyein Oguzhan Kaya Electrochemical Biosensors for Healthcare Applications
16.25-16.35	YS 14 – Fatma Kurul Advancing Single Cell Growth Measurement: A Plasmonic Functional Assay Platform with Refractive Index Sensing	YS 29 – Ayse Nur Buke Determination of The Dissolution of Hypericin From Polymeric Nanoparticles by HPLC Analysis	YS 44 – Marina Serin Development of a prototype biosensor to determine the severity of demyelination due to diabetic neuropathy in serum
16.35-16.45	YS 15 – İbrahim Gadashli Comparison of antibody and lobaric acid small molecule application in the treatment of ovarian cancer at the transcriptome level in the IL-6R / STAT3 / PD-L1 pathway	YS 30 – Sinem Demir Drug release profles of Atenolol and Benidipine from pH‑responsive polymeric hydrogel matrix	YS 45 – Ozum Ozoglu
16.45-16.55			YS 46 – Ümmüye Nur Tüzün Electrochemical development of poly(L-alanine)-gold nanoparticles-modified electrode for the determination and mechanism of antipsychotic drug olanzapine
17.30-18.15	Ottoman Band and Traditional Dance Show
19.30-22.00	Gala Dinner

July 6, 2023
	Hall A
09.00-09.45	PL 6 – Maria Montes Bayon Bioanalytical tools to evaluate the capabilities of iron oxide nanoparticles decorated with cisplatin (IV) as drug delivery systems in cell models.
09.45-10.00	Coffee Break
	Hall A	Hall B
10.00-10.30	KL 27 – Elia Psillakis Designing for a green analytical chemistry future	KL 28 – Alberto Escarpa Micromotors in action: smart microsensors swimming in a concept or a futuristic reality?
10.30-11.00	KL 29 – Caterina Temporini Challenges and Advances in Extracellular Vesicles Analysis	KL 30 – Suna Timur Biofunctional Nanostructures, In vitro Diagnostics Platforms
11.00-11.15	OP 52 – Erica Aparecida Souza Silva Chloroformate derivatization combined with HS-SPME-GC/MS for determination of SCFAs in mice liver: a proof of concept	OP 53 – Aysegul Golcu Investigation of binding constants of some small molecules to deoxyribonucleic acid in solution medium
11.15-11.30	OP 54 – Zahirul Kabir On the transport of an anticancer drug, leflunomide in human blood circulation as studied by multi-spectroscopic and computational investigations.	OP 55 – Bilal Kızılelma Carbon based electrochemical immunosensor for malignant tumors marker anti-SOX2 detection
11.30-11.45	OP 56 – Nejla Cini pH-Responsive Poly(Acrylic Acid) Hydrogel Systems for Controlled Release of a Dihydropyridine Type Calcium Antagonist	OP 57 – Zeynep Aydoğmuş Electrochemical design of two new sensors based on graphene nanoparticles and polymer resin -modified carbon paste electrodes for the determination of Tenofovir and Entecavir
11.45-12.00	OP 58 – Kemal Çetin Production of a hybrid structure consisting of polycaprolactone electrospun nanofiber and poly(2-hydroxyethyl methacrylate)-based cryogel for 5-fluorouracil release	OP 59 – Elif Burcu Aydin A label-free electrochemical magneto immunosensor for celiac disease
12.00-12.15	OP 60 – Zeynep Kalaycıoğlu The affinity of dopamine and serotonin to serum albumin: Capillary electrophoresis-frontal analysis and in-silico molecular docking approaches	OP 61 – Ece Ozkan
12.15-13.00	Lunch
	Hall A
13.00-13.30	KL 31 – Salvatore Fanali Nano-liquid chromatography: recent advances in chiral analysis
13.30-14.00	Closing Ceremony

Scientific Program - Draft